I’ve migrated another paper to E-drexler.com:
Drexler, KE. “Molecular Nanomachines: Physical Principles and Implementation Strategies”, Annual Review of Biophysics and Biomolecular Structure, 23:377-405 (1994).
(With thanks to Robert Bradbury for the original HTML conversion.)
See also:
- The Physical Basis of Atomically Precise Manufacturing
- A Telescope Aimed at the Future
- Productive nanosystems: the physics of molecular fabrication [pdf]
(from the Institute of Physics journal, Physics Education)



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Do you agree with Ray Kurzweil’s wild speculation about the future of nanotechnology?. Ideas like: Billions of nanobots in our brain will make us a billion times more intelligent.
Miguel — In Engines of Creation (1986) I surveyed some of what one might expect to be able to do with advanced nanotechnologies developed using capabilities that would rely on advanced, atomically precise fabrication; this included biomedical-spectrum applications. I haven’t revisited the area in the last decade or two, however.
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