From the category archives:

Structure of knowledge

High-school civics and minds,
1890 and now

September 2, 2010

A comment on my recent post, “The problem: a metacognition deficit,” reminded me of a striking illustration of cultural change, the level of the language and content of a book used in the 1890s to teach high school civics (available in plain text, a big pdf and simulated in-browser book ). It reeks of a [...]

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The problem: a metacognition deficit

August 27, 2010

…there’s a metacognition deficit. Very few in public life habitually step back and think about the weakness in their own thinking and what they should do to compensate…
Of the problems that afflict the country, this is the underlying one.
David Brooks, (“A Case of Mental Courage”, New York Times)
Brooks begins with the story of how [...]

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How to Learn about Everything in Belorussian

August 25, 2010

“How to Learn about Everything”, now in Belorussian translation:
       
(With thanks to Patricia Clausnitzer!)

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“The China Study” Considered Harmful

July 11, 2010

An influential study of diet and health has been exploded here. The data and the conclusions don’t just disagree, they aren’t even on speaking terms.

Meanwhile, randomized intervention trials indicate that advice on the perils of saturated fat has been wrong. I suggest some reforms.

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Data-mining the bioscience literature

June 24, 2010

Genomics, transcriptomics, proteomics, and metabolomics now meet paperomics: Automated trawling, not of whole slices of nature, but of whole slices of the scientific literature — the idea is to look for indirect links among papers that may indicate undiscovered links in nature.
From the Computable Genomix website:
…Powered by patent pending next generation text mining technology, GeneIndexer [...]

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Inquiry in Engineering, Design in Science:
Completing the Matrix

June 7, 2010

The focus of science is inquiry, and the focus of engineering is design. Just as sensory and motor neurons run antiparallel through the structure of the body, so inquiry and design run antiparallel through the structure of knowledge. Eye and hand, perception and action, measuring and making, science seeking knowledge, engineering seeking function.
I’ve been exploring [...]

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Knowledge and causality in inquiry and design

June 3, 2010

The structure of science and engineering, a big mistake, and a book

See also: “The Antiparallel Structures of Science and Engineering”

An effect may have one possible cause, or many. The weight of a stone has a single cause, gravity, but the flight of a stone coming over a wall could have one of many [...]

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Reshaping airframes & expectations

May 17, 2010

Like most people with a conservative engineering mindset, I usually assume that major commercial technologies are designed to work reasonably close to the limits of current fabrication technologies (currently practical materials, subsystem performance, etc.). Then something like this comes along:
…an MIT-led team has designed a green airplane that is estimated to use 70 percent less [...]

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Is 华大基因 doing science?
     (aka BGI)

March 18, 2010

In a decade, the global Human Genome Project sequenced 3 billion DNA base pairs. Today, a single machine (the Illumina HiSeq™ 2000) can sequence 25 billion base pairs per day, and BGI (the Shenzhen company formerly known as the Beijing Genomics Institute) has purchased 128 of them. This puts BGI “on track to surpass [...]

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Learning Bioinformatics

March 12, 2010

Bioinformatics is huge, growing, fast, and has a surprising range of applications to molecular systems engineering. Here’s a PLoS article: “A Quick Guide for Developing Effective Bioinformatics Programming Skills”. From the abstract:
Successful adoption of these principals will serve both beginner and experienced bioinformaticians alike in career development and pursuit of professional and scientific goals.

[...]

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How to study for a career in nanotechnology

February 24, 2010

Students often ask me for advice on how to study for a career in nanotechnology, and as you might imagine, providing a good answer is challenging. “Nanotechnology” refers to a notoriously broad range of areas of science and technology, and progress during a student’s career will open new areas, and some are yet to be [...]

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Chemists deserve more credit:
Atoms, Einstein, and the Matthew Effect

February 17, 2010

Chemists understood the atomic structure of molecules in the 1800s, yet it is often said that Einstein established the existence of atoms in a paper on Brownian motion, “Die von der Molekularkinetischen Theorie der Wärme Gefordete Bewegung von in ruhenden Flüssigkeiten Suspendierten Teilchen”, published in 1905.
This is perverse, and has seemed strange to me [...]

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